C8A ELISA Kit for Rabbit(Oryctolagus cuniculus) | EIAab.comC8A ELISA Kit for Rabbit(Oryctolagus cuniculus)

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Index > Protein center > C8A(Gene name) > Rabbit

C8A (Gene name),

Complement component C8 alpha chain (Protein name ), CO8A_RABIT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

C8A;

Protein name:

Complement component C8 alpha chain;

Alternative:

Complement component 8 subunit alpha;

Organism:

Rabbit (Oryctolagus cuniculus).

General Annotation

Sub Unit:

Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.

Function:

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.

Subcellular Location:

Secreted Cell membrane Multi-pass membrane protein Secreted as soluble protein. Inserts into the cell membrane of target cells.

Protein Attributes:

Sequence length:

585

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

585:

PCTAGTRERR | RECNNPAPQN | GGAPCPGWRV | QTQAC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P98136

UniGene:

Ocu.1990

SMR:

P98136

Pfam:

PF00057

STRING:

9986.ENSOCUP00000014764

Uniprot:

P98136

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ELISA Kit for Rabbit Complement component C8 alpha chain

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ELISA Kit for Rabbit Complement component C8 alpha chain

Cat.:

E1970h

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Rabbit Complement component C8 alpha chain

Cat.:

E1970m

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MSDS:

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Packing:

96T

CLIA Kit for Rabbit Complement component C8 alpha chain

Cat.:

U1970m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rabbit Complement component C8 alpha chain

Cat.:

U1970h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rabbit Complement component C8 alpha chain

MSDS:

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Polyclonal Antibody for Rabbit Complement component C8 alpha chain

Cat.:

P1970Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rabbit Complement component C8 alpha chain

Cat.:

P1970Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rabbit Complement component C8 alpha chain

Protein for Rabbit Complement component C8 alpha chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of rabbit complement component C8. Functional evidence for the species-selective recognition of C8 alpha by homologous restriction factor (CD59)."
White R.V. , Kaufman K.M. , Letson C.S. , Platteborze P.L. , Sodetz J.M.
J. Immunol.152:2501-2508(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 31-40;SUBUNIT;SUBCELLULAR LOCATION
strain: New Zealand white.
tissue: Liver.

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